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Airway pressure release ventilation for in-vivo donor lung management and lung transplant outcomes

   
@article{CJTS45577,
	author = {Sreeja Biswas Roy 和 Deepika Razia 和 Ashwini Arjuna 和 Paul Kang 和 Michael T. Olson 和 Ross M. Bremner 和 Michael A. Smith 和 Rajat Walia},
	title = {Airway pressure release ventilation for  in-vivo  donor lung management and lung transplant outcomes},
	journal = {中华胸部外科电子杂志},
	volume = {9},
	number = {2},
	year = {2022},
	keywords = {},
	abstract = {Background: Airway pressure release ventilation (APRV) can be used for cadaveric donor lung recruitment. APRV elevates PaO2 in donor lungs; however, reported outcomes in recipients with APRV-managed donor lungs are limited. Methods: We retrospectively reviewed patients who underwent lung transplantation (LTx) from 2012 to 2013 and divided them into two groups based on mode of ventilation used during donor management and organ extraction (A: non-APRV; B: APRV). Kaplan-Meier method and multivariate Cox regression were used for analysis. Results: We found 126 LTx recipients (LTxRs); 9 were excluded for use of portable ventilation perfusion systems. Of the remaining 117 patients, 81 (69%) were in Group A; 36 (31%) were in Group B. Preoperative LTxR characteristics (age, sex, lung allocation score, end-stage lung disease type) were comparable between groups. Donors for Group B were older (P=0.03) and had higher body mass index (BMI) (P},
	url = {https://www.thecjts.cn/article/view/45577}
}